About us

Renāte Ranka , Dr. biol

Leading researcher
Phone: +371 67808218
E-mail: renate_r@biomed.lu.lv

Groups

• R. Ranka lab

Projects

• The impact of burial environmental microbiome on biomolecular archeology and the ancient tuberculosis research
• Assessment of magnitude and importance of vectorborne Babesiosis in Latvia: epidemiological and diagnostic approach
• Paleopathological and molecular genetic studies of anthropological materials obtained from archaeological excavations in a territory of Latvia
• Searching for Innovative Strategies of Regulation and Modulation of Infection Mechanisms

Publications

• International

• Mitochondria, its DNA and telomeres in ageing and human population. E Zole, R Ranka , Biogerontology, Feb 28. doi: 10.1007/s10522 018-9748-6. [Epub ahead of print] Review. PMID: 29488130 , 2018
• Pediatric and adolescent tuberculosis in Latvia, 2011-2014: Case detection, diagnosis and treatment Ziemele, B., R Ranka, Ozere, I. , International Journal of Tuberculosis and Lung Disease, 21 (6), pp. 637-644 , 2017
• Linkage between mitochondrial genome alterations, telomere length and aging population E Zole, Zadinane, K., L Pliss, R Ranka , Mitochondrial DNA Part A: DNA Mapping, Sequencing, and Analysis, pp. 1-8 , 2017
• The effect of glaucoma filtration surgery on structural and functional eye parameters in a short-term study Baumane, K.,, R Ranka, Laganovska, G , Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences, 71 (1-2), pp. 27-32 , 2017
• Prevalence and phylogenetic analysis of Babesia spp. in Ixodes ricinus and Ixodes persulcatus ticks in Latvia V Čapligina, Berzina, I., Bormane, A., Salmane, I., Vilks, K., A Kazarina, Bandere, D., V Baumanis, R Ranka , Experimental and Applied Acarology, 68 (3), pp. 325-336 , 2016
• Fatal Babesia canis canis infection in a splenectomized Estonian dog Tiškina, V., V Čapligina, Must, K., Berzina, I., R Ranka, Jokelainen, P. , Acta Veterinaria Scandinavica , 2016
• Latin-American-Mediterranean lineage of Mycobacterium tuberculosis: Human traces across pathogen's phylogeography Mokrousov, I., Vyazovaya, A., Iwamoto, T., Skiba, Y., I Pole, Zhdanova, S., Arikawa, K., Sinkov, V., Umpeleva, T., Valcheva, V., Alvarez Figueroa, M., R Ranka, I Jansone, Ogarkov, O., Zhuravlev, V., Narvskaya, O. , Molecular Phylogenetics and Evolution, 99, pp. 133-143 , 2016
• MIRU-VNTR genotype diversity and indications of homoplasy in M. avium strains isolated from humans and slaughter pigs in Latvia Kalvisa, A., Tsirogiannis, C., I Silamiķelis, Skenders, G., Broka, L., Zirnitis, A., I Jansone, R Ranka , Infection, Genetics and Evolution, 43, pp. 15-21 , 2016
• Genotype and allele frequencies of isoniazid-metabolizing enzymes NAT2 and GSTM1 in Latvian tuberculosis patients V Igumnova, V Čapligina, Krams, A., Cirule, A., Elferts, D., I Pole, I Jansone, Bandere, D., R Ranka , Journal of Infection and Chemotherapy, 22 (7), pp. 472-477 , 2016
• Association of NT-proANP Level in Plasma and Humor Aqueous with Primary Open-Angle Glaucoma Baumane, K., R Ranka, Laganovska, G. , Current Eye Research, pp. 1-4 , 2016
• Comparison of telomere length between population-specific mitochondrial haplogroups among different age groups in a Latvian population E Zole, Elfers, D., J Ķimsis, A Krūmiņa, Narels, K., I Pole, R Ranka, L Pliss , Mechanisms of Ageing and Development, 145, pp. 13-17 , 2015
• Morphological characterisation and molecular sex determination of human remains from the 15th-17th centuries in Latvia Ščėsnaitė-Jerdiakova, A., L Pliss, Gerhards, G., Gordina, E.P., Gustiņa, A., I Pole, E Zole, J Ķimsis, I Jansone, R Ranka , Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences, 69 (1-2), pp. 8-13 , 2015
• Structural characterization of CspZ, a complement regulator factor H and FHL-1 binding protein from Borrelia burgdorferi. K Brangulis, I Petrovskis, A Kazāks, J Bogans, Otikovs M, Jaudzems K, R Ranka, K Tārs , FEBS J., 281(11):2613-22 , 2014
• Anaplasma phagocytophilum DNA amplified from lesional skin of seropositive dogs. Berzina I, Krudewig C, Silaghi C, Matise I, R Ranka, Müller N, Welle M , Ticks Tick Borne Dis. 5(3):329-35 , 2014
• Genotypic and phenotypic characteristics of aminoglycoside-resistant Mycobacterium tuberculosis isolates in Latvia. M Baušķenieks, I Pole, Skenders G, I Jansone, Broka L, Nodieva A, Ozere I, A Kalviša, R Ranka, V Baumanis , Diagn Microbiol Infect Dis. 81(3):177-82 , 2014

• Local

• Analysis of the seroreactivity to recombinant B. burgdorferi antigens BBA65 and BBA73. R Ranka, Muzje G, K Brangulis, I Petrovskis, K Vilks, V Čapligina , RSU Collection of Scientific Papers 2014, Research articles in medicine & pharmacy, 40-46 p , 2014
• Cloning and expression of a recombinant immunogenic truncated BBK32 protein of Borrelia afzeli. R Ranka, V Čapligina, K Brangulis, Sondore V, V Baumanis , Acta Universitatis Latviensis 753: 33–42 , 2009
• Prevalence of varios Borrelia burgdorferi sensu lato species in Ixodes ticks in three Baltic countries. R Ranka, K Salmiņa, Zygutiene M, Morkunas B, Bormane A, V Baumanis , Acta Universitatis Latviensis 662: 7-15 , 2003
• Incidence of Borrelia Burgdorferi infected ticks in Latvia. V Baumanis, J Kloviņš, R Ranka, Vetcmane-Vetce K, Puzuka A, Lavrinoviča M, Bormane A, Kalniņa V , Proc. Latvian Acad. Sci. 4: 21-29 , 2001
• Incidence of Borrelia Burgdorferi infected ticks in Latvia and their molecular typing. V Baumanis, J Kloviņš, R Ranka, Vetcmane-Vetce K, Puzuka A, Lavrinoviča M, Bormane A, Kalniņa V , Proc. Latvian Acad. Sci. 55: 164-170 , 2001

• Conference thesis

• Crystal structure of the B. Burgdorferi outer surface protein of the paralogous gene family PFam5 R Ranka, K Brangulis, K Tārs, I Petrovskis, V Baumanis , Gordon Research Conferences frontiers of science, Venturi, ASV , 2014
• Evaluation of ancient DNA preservation by applying molecular approach for sex determination in archaeological human skeletal remains from Riga. A.Ščėsnaitė-Jerdiakova, L Pliss, G.Gerhards, E.Pētersone-Gordina, I Pole, E Zole, J Ķimsis, A Gustiņa, R Ranka, I Jansone , 3rd Baltic Bioarchaeology Meeting, Rīga, Latvija , 2014
• Diversity and spreed of Mycobacteium tuberculosis strains in Riga and its surroundings in Years 2009 - 2012 I Pole, I Jansone, Ģ.Šķenders, J.Trofimova, A.Nodieva, I.Ozere, V.Riekstiņa, P.Supply, E.Willery, S.Lecher, J.Storozenko, L.Vīksna, V.Leimane, R Ranka, V Baumanis , 35th Annunal Congress of the European Society of Mycobacteriology, Vīne, Austrija , 2014
• The level of relatedness among homoplasic MIRU-VNRT profiles of modelled Mycobacterium avium genotype populations. Pp91. A Kalviša, C.Tsirogiannis, L Pliss, I Silamiķelis, R Ranka , 35th Annual congress of the European Society of Mycobacteriology, Vīne, Austrija , 2014
• Comparison of several molecular processing approaches of ancient DNA from medieval human remains in Latvia R Ranka, L Pliss, E Zole, I Pole, A.Ščesnaite-Jerdiakova, J Ķimsis, G. Gerhards, E.Pētersone-Gordina, I Jansone , FEBS conference, Parīze, Francija , 2014
• The epidemiological studies of tuberculosis in Latvian children I Jansone, A.Nodieva, I.Ozere, R Ranka, I Pole, G.Šķenders , 45th Union World Conference on Lung Health, Barselona, Spānija , 2014
• Successful creation of chimeric virus-like particles maintaining fibronectin-binding property from B.burgdorferi BBK32 protein R Ranka, I Petrovskis, I Sominska, K Brangulis, P Pumpēns, V Baumanis , XII International Jena Symposium on Tick-borne Diseases. Weimar, Vācija , 2013
• Study of B. burgdorferi outer membrane proteins by protein-protein interaction approach R Ranka, K Vilks, K Brangulis, I Petrovskis, V Čapligina, V Baumanis , 38th FEBS Congress, St.Petersburg, Krievija. , 2013
• Telomere length between mononuclear blood cells (MNC) and peripheral white blood cells (WBC) in context with population-specific mitochondrial (MT) lineages in a Latvian population ageing E Zole, L Pliss, R Ranka, A Krūmiņa, V Baumanis , 38th FEBS Congress, St.Petersburg, Krievija. , 2013
• Ērču encefalīta vīrusa RNS noteikšana migrējošo putnu ērcēs Latvijā Japiņa K, Keišs O, Salmane I, R Ranka, V Baumanis , RSU studentu zinātniskā konference, stenda referāts. , 2013
• Dissemination of Lyme disease agents in Eupope by migratory birds. R Ranka, V Čapligina, Keiss O, K Brangulis, K Vilks, V Baumanis , 1st Congress of Baltic Microbiologists, Riga. Book of abstracts, p. 06 , 2012
• Telomeres length variation in different age groups in Latvian population. L Pliss, E Zole, R Ranka, J Ķimsis, Aitullina A, A Krūmiņa, V Baumanis , Vth Interantional School of Molecular genetics “Changing genome”, Moscow-Zvenigorod. Abstracts p. 8. , 2012
• Crystal structure of an outer surface protein BBA64 from Borrelai burgdorferi in comparison to BbCRASP-1. K Brangulis, K Tārs, I Petrovskis, R Ranka, V Baumanis , The FEBS Journal, v.279, S.1, p.467 , 2012
• The study of genetic factors in primary open-angle glaucoma patients in Latvia. R Ranka, A Gustiņa, Baumane K, L Pliss, Laganovska G, V Baumanis , The FEBS Journal, v.279, S.1, p.307 , 2012
• Increased mitochondrial DNA (mtDNA) heteroplasmy in aged person groups and approaches of its analysis. K Vilks, L Pliss, E Zole, R Ranka, A Krūmiņa, V Baumanis , Abstracts of IMBG conference. Molecular Biology advances and perspectives. Kiiv, Ukraine , 2011

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