Research Directions and labs
Research
Biotechnology and structural biology

K. Tars lab

Kaspars Tārs , Dr. biol.

Study Director/Senior researcher
Phone: +371 67808200
E-mail: kaspars@biomed.lu.lv

Andris Kazāks , Dr. biol.

Senior researcher
Phone: +371 67808200
E-mail: andris@biomed.lu.lv

Research

The main research area of our group is devoted to single stranded RNA bacteriophages and their virus-like particles (VLPs). In our lab we are extensively studying genomes, structures and molecular interactions of numerous RNA phages. Our work has resulted both in deeper understanding of phage molecular biology and several applications of their VLPs, the most important of which lies in vaccine development.

Since our lab is the only one in Latvia with a capability to determine protein crystal structures, we have several other projects, mostly aimed towards structure-based inhibitor design against various pharmacologically relevant enzymes. Those projects are done on collaboration basis with Institute of Organic Synthesis, performing synthesis of the inhibitory compounds. Our most important targets include carbonic anhydrases and enzymes, involved in carnitine and trimethylamine metabolism.

Our research group has been formed by creating a tandem of two former research groups, led by Dr. Kaspars Tārs and Dr. Andris Kazāks. Kaspars Tārs has the necessary expertise in structural biology, while Andris Kazāks is an expert in protein production and purification. 

Scientific Staff

Tatjana Kazāka , Dr. biol., tatyanav@biomed.lu.lv

Tatjana Kazāka , Dr. biol.

Senior researcher
Phone: +371 67808200
E-mail: tatyanav@biomed.lu.lv

Jānis Rūmnieks , Dr. biol., j.rumnieks@biomeb.lu.lv

Jānis Rūmnieks , Dr. biol.

Researchers
Phone: +371 67808200
E-mail: j.rumnieks@biomeb.lu.lv

Ināra Akopjana , in.ak@inbox.lv

Ināra Akopjana

Scientific assistant
Phone: 67808213
E-mail: in.ak@inbox.lv

Svetlana Koteloviča , MSc. biol., sveta@biomed.lu.lv

Svetlana Koteloviča , MSc. biol.

Research assistants
Phone: +371 67808200
E-mail: sveta@biomed.lu.lv

Gints Kalniņš , MSc. biol., gints.kalnins@biomed.lu.lv

Gints Kalniņš , MSc. biol.

Research assistants
Phone: +371 67808221
E-mail: gints.kalnins@biomed.lu.lv

Jānis Leitāns , MSc. biol., janisl@biomed.lu.lv

Jānis Leitāns , MSc. biol.

Research assistants
Phone: +371 67808200
E-mail: janisl@biomed.lu.lv

Mihails Šisovs , BSc. biol., mihails.shishovs@gmail.com

Mihails Šisovs , BSc. biol.

Laboratory assistant
Phone: +371 67808200
E-mail: mihails.shishovs@gmail.com

Elīna Černooka , MSc. biol., elina.cernooka@biomed.lu.lv

Elīna Černooka , MSc. biol.

Laboratory assistant
Phone: +371 67808200
E-mail: elina.cernooka@biomed.lu.lv

Anna Kiršteina , BSc. biol., anna.kirsteina@gmail.com

Anna Kiršteina , BSc. biol.

Laboratory assistant
Phone: +371 67808200
E-mail: anna.kirsteina@gmail.com

Cooperation partners

International:

National:

Publications


All publications

Quick links

Group quick links

Current Projects


All group projects


Mājas lapas izstrādi finansēja ERAF 2.1.1.2. aktivitātes projekts Nr. 2010/0196/2DP/2.1.1.2.0/10/APIA/VIAA/004 "Latvijas biomedicīnas pētījumu integrācija Eiropas zinātnes telpā".