Research Directions and labs
Research
Cancer research

A. Linē lab

Aija Linē , Dr. biol.

Scientific director / Senior researcher
Phone: +371808208
E-mail: aija@biomed.lu.lv

Research

The main focus of our group is the discovery and validation of blood-based biomarkers for the early detection, monitoring and prognosis of cancer. Historically, the first object we were working on was autoantibodies against tumour antigens. We exploited our Cancer Antigen Collection comprising >1800 antigens and antigen microarray technology to evaluate their relevance for detection and prognosis of gastric, thyroid, prostate and breast cancer. Currently, our main   research area is investigation of the molecular content, functional role and therapeutic applications of cancer-derived extracellular vesicles. Furthermore, we have started a project aiming to develop a precision medicine test for molecular profiling of breast cancer that helps to choose the best treatment option for each patient and a personalised liquid biopsy for monitoring the treatment response and early detection of recurrence. 

 

Cooperation partners:

  

  

  

 

 

 

 

  

 

Scientific Staff

Pavels Zajakins , Dr. biol., pz@magisters.net

Pavels Zajakins , Dr. biol.

Researcher
Phone: +371 67808200
E-mail: pz@magisters.net

Artūrs Ābols , Dr. biol., arturs@biomed.lu.lv

Artūrs Ābols , Dr. biol.

Researcher
Phone: +371 67808208
E-mail: arturs@biomed.lu.lv

Moto: How we spend our days is, of course, how we spend our lives. /Annie Dillard/

Andreas Berger , MSc. biol., andreas.berger@biomed.lu.lv

Andreas Berger , MSc. biol.

Research assistants
Phone: +371 67808208
E-mail: andreas.berger@biomed.lu.lv

Edgars Endzeliņš , MSc. biol., edgars.endzelins@gmail.com

Edgars Endzeliņš , MSc. biol.

Research assistants
Phone: +371 67808208
E-mail: edgars.endzelins@gmail.com

Cristina Bajo Santos , MSc. biol., crisbs88@hotmail.com

Cristina Bajo Santos , MSc. biol.

Research assistants
Phone: +371 67808208
E-mail: crisbs88@hotmail.com

Lilite Sadovska , MSc. biol., lilite@biomed.lu.lv

Lilite Sadovska , MSc. biol.

Research assistants
Phone: +371 28222543
E-mail: lilite@biomed.lu.lv

Kristīne Soboļevska , BSc. biol., k.sobolevska@gmail.com

Kristīne Soboļevska , BSc. biol.

Laboratory assistant
Phone: +371 67808200
E-mail: k.sobolevska@gmail.com

Artūrs Bušs

Artūrs Bušs

Laboratory assistant
Phone: +371 67808208

Publications


All publications

Quick links

Group quick links

Current Projects


All group projects

Latest activities

A review on Diagnostic, prognostic and predictive value of cell-free miRNAs in prostate cancer is published in Molecular Cancer (IF=5.888).
The results obtained within The National Research Program BIOMEDICINE on the role of CAIX in the induction of immunosuppressive microenvironment in breast cancer were presented at 2nd Symposium on Advances in Cancer Immunology and Immunotherapy in Athens and obtained the 2nd award in the poster competition
Our latest paper on the characterisation of IgG and IgA repertoire in breast cancer tissues is accepted for publication in Frontiers in Immunology.


Mājas lapas izstrādi finansēja ERAF 2.1.1.2. aktivitātes projekts Nr. 2010/0196/2DP/2.1.1.2.0/10/APIA/VIAA/004 "Latvijas biomedicīnas pētījumu integrācija Eiropas zinātnes telpā".