Paleopathological and molecular genetic studies of anthropological materials obtained from archaeological excavations in a territory of Latvia
Title of the Project: “Paleopathological and molecular genetic studies of anthropological materials obtained from archaeological excavations in a territory of Latvia.”
The Project is performed under European Social Fund (ESF) project Program "Human resources and employment" activity 220.127.116.11. "Involvement of human resources in science"
Identification no. of the Project: 2013/0039/1DP/18.104.22.168.0/13/APIA/VIAA/038
Implementation time-limit of the Project: 20 months (1st January, 2014 – 31st of August, 2015)
Participating institutions in realization of the Project: APP Latvian Biomedical Research and Study Centre (BMC), LU Agency LU Institute of Latvian History (LUVI)
Total funding of the Project: 480 190,78 EUR (BMC – 405 467,24 EUR, LUVI – 74 723,54 EUR)
Scientific supervisor of the Project: Dr.biol. R.Ranka
The main goal of the Project is establishment of a new scientific group that could be able to solve with medicine connected problems in Latvia using modern molecular biology approaches. The Project is multidisciplinary and involves participants from different branches: biology, archaeology and history.
Researches on ancient DNA mostly include phylogenetic studies and molecular medicine archaeology.
Under the Project the following activities are planned: (1) establishment of a new scientific group; (2) evaluation of DNA quality isolated from archaeological materials and it further usage for detailed studies; (3) molecular genetic studies of potential infectious agents and genetic variability of the medieval population inhabited a territory of Latvia; (4) human genetic studies that are going to be applied for elucidation of ancient and nowadays population genetic differences/similarities based on variation mitochondrial DNA (mtDNA) and Y chromosomal haplotypes. In addition, spectrum of mtDNA polymorphisms and mutations will be evaluated in samples. Moreover, a new technology (a protocol) for detection of mtDNA and Y chromosomal genetic profiles from human osteomaterials (bones) will be established for forensic cases.