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Prognostic testing for assessment of the effectiveness of immunotherapeutic drugs: method for personalized drug usage in oncology

Project is carried out within the European Regional Development Fund (ERDF) activity "Support for science and research"
Project identification number: 2010/0233/2DP/2.1.1.1.0/10/APIA/VIAA/076
Project activity period: 36 months (01.10.2010.-30.09.2013.)

Project funds: LVL 294,938.00
Principle investigator: Dr. biol. Dace Pjanova

General aim of the project: improved effectiveness of immunotherapy of oncologic patients.

Specific aim of the project: development of a personalized prognostic in vitro testing method for assessment of the effectiveness of immunotherapeutic drug before starting the immunotherapy.

Activities implemented during the project:

1.   Research:

1.1. determination of lymphocyte sub-populations induced by the drugs,

1.2. determination of the activity of lymphocytes induced by the drugs,

1.3. identification of the drugs' induced expansion of the lymphocytes in individual sub-populations and determination of their activity in different groups of oncologic patients,

1.4. development of a personalized prognostic in vitro testing method of the effect of immunotherapeutic drugs.

2. Providing of public availability of the research results.

Expected result of the project. Personalized prognostic in vitro testing method for assessment of the effectiveness of immunotherapeutic drug before starting the immunotherapy for the use in the oncology. Detailed description of the method.



Mājas lapas izstrādi finansēja ERAF 2.1.1.2. aktivitātes projekts Nr. 2010/0196/2DP/2.1.1.2.0/10/APIA/VIAA/004 "Latvijas biomedicīnas pētījumu integrācija Eiropas zinātnes telpā".