Research Publications

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All International Local Patents Monographs Conference thesis
Name Authors Published in Year Internet
Pyrrolomycins as antimicrobial agents. Microwave-assisted organic synthesis and insights into their antimicrobial mechanism of action Raimondi, M.V., Listro, R., Cusimano, M.G., La Franca, M., Faddetta, T., Gallo, G., Schillaci, D., Collina, S.,, A Leončiks, Barone, G. Bioorganic and Medicinal Chemistry, 27 (5), pp. 721-728. PMID: 30711310 2019
Expression of the chemokine receptors CCR1 and CCR2B is up-regulated in peripheral blood B cells upon EBV infection and in established lymphoblastoid cell lines Kholodnyuk, I., Ž Rudevica, A Leončiks, Ehlin-Henriksson, B., Kashuba, E Virology, 512, pp. 1-7 2017
Discovery of a New Class of Sortase A Transpeptidase Inhibitors to Tackle Gram-Positive Pathogens: 2-(2-Phenylhydrazinylidene)alkanoic Acids and Related Derivatives Maggio B, Raffa D, Raimondi MV, Cascioferro S, Plescia F, Schillaci D, Cusimano MG, A Leončiks, D Žuļenkovs, Basile L, Daidone G. Molecules. 2016 Feb 19;21(2):241 2016
A new class of phenylhydrazinylidene derivatives as inhibitors of Staphylococcus aureus biofilm formation Cascioferro S, Maggio B, Raffa D, Raimondi MV, Cusimano MG, Schillaci D, Manachini B, A Leončiks, Daidone G. Medicinal Chemistry Research. (2016) May 1;25(5):870-878 2016
Comparative protein profiling of B16 mouse melanoma cells susceptible and non-susceptible to alphavirus infection: Effect of the tumor microenvironment J Vasiļevska, De Souza, G.A., Stensland, M., D Skrastiņa, D Žuļenkovs, Paplausks, R., B Ķūrēna, T Kozlovska, A Zajakina Cancer Biology and Therapy, 17 (10), pp. 1035-1050 2016
Synthesis and Antibacterial Activity of 5-Phthalate and 5-Glutarate Derivatives of Milbemycins Lugiņina, J., Bizděna, E., A Leončiks, Kumpiņš, V., Grinšteine, I., Turks, M. Chemistry of Heterocyclic Compounds, 50 (10), pp. 1404-1412 2015
Synthesis, structure and biological activity of new 6,6-dimethyl-2-oxo-4-{2-[5-organylsilyl(germyl)]furan(thiophen)-2-yl}vinyl-5,6-dihydro-2H-pyran-3-carbonitriles Ignatovich, L., Spura, J., Muravenko, V., Belyakov, S., Popelis, J., Shestakova, I., Domrachova, I., Gulbe, A., Ž Rudevica, A Leončiks Applied Organometallic Chemistry, 29 (11), pp. 756-763 2015
Selenopheno[3,2-c]- and [2,3-c]coumarins: Synthesis, cytotoxicity, angiogenesis inhibition, and antioxidant properties Arsenyan, P., Vasiljeva, J., Shestakova, I., Domracheva, I., Jaschenko, E., Romanchikova, N., A Leončiks, Ž Rudevica, Belyakov, S. Comptes Rendus Chimie, 18 (4), art. no. 3984, pp. 399-409 2015
Enzymatic activity of circular sortase A under denaturing conditions: An advanced tool for protein ligation. D Žuļenkovs, Jaudzems K, A Zajakina, A Leončiks Biochemical Engineering Journal. 82(15):200–209 2014
Structural characterization of CspZ, a complement regulator factor H and FHL-1 binding protein from Borrelia burgdorferi. K Brangulis, I Petrovskis, A Kazāks, J Bogans, Otikovs M, Jaudzems K, R Ranka, K Tārs FEBS J., 281(11):2613-22 2014
High efficiency of alphaviral gene transfer in combination with 5-fluorouracil in a mouse mammary tumor model. A Zajakina, J Vasiļevska, D Žuļenkovs, D Skrastiņa, Spaks A, Plotniece A, T Kozlovska BMC Cancer. 14:460 2014
Mosaic RNA phage VLPs carrying domain III of the West Nile virus E protein. I Cielēns, L Jackeviča, A Strods, A Kazāks, V Ose-Klinklāva, J Bogans, P Pumpēns, R Renhofa FEBS J. 281(11):2613-22 2014
Discovery and structure-activity relationship studies of irreversible benzisothiazolinone-based inhibitors against Staphylococcus aureus sortase A transpeptidase. D Žuļenkovs, Ž Rudevica, Jaudzems K, Turks M, A Leončiks Bioorg Med Chem. 22(21):5988-6003 2014
Synthesis of quinazolinone-1,3,4-oxadiazole conjugates and studies of their antibacterial and antioxidant activity. Zicane D, Tetere Z, Mierina I, Turks M, Ravina R, A Leončiks Journal of Chemical and Pharmaceutical Research. 6(4):1153-1158 2014
Screening of staphylococcus aureus sortase a inhibitors: novel antibiotic drug design D Žuļenkovs, A Zajakina, K. Jaundzems, A Leončiks Химия структура и функция биомолекул, Minska, Baltkrievija 2014
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